Synthetic seven-amino-acid peptide based on a fragment of ACTH — studied in nootropic and neuroprotection research.
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Semax is a seven-amino-acid synthetic peptide developed at the Russian Academy of Medical Sciences. It's built from a small fragment of ACTH (a stress hormone), with a stabilizing three-amino-acid tail (PGP) added on. Importantly, Semax keeps the brain-relevant activity of that ACTH fragment without driving the stress-hormone system itself.
How it's been studied: Lab research has examined how Semax influences brain growth factors like BDNF and NGF, how it engages the MC4R melanocortin receptor without triggering ACTH-like effects, and how it affects dopamine and serotonin signaling.
Where you'll see it in research:
Handling notes: The PGP tail provides resistance to enzyme breakdown — significantly more stable than the natural ACTH fragment.
Every batch is third-party tested for purity, identity, and contaminants. Download the COA for the lot you receive.
Molecular Weight
813.94 g/mol
Form
Lyophilized powder
Storage
Lyophilized: 2-8°C up to 24 months. Reconstituted: 2-8°C, use within 30 days.
Sequence
MEHFPGP
All compounds are sold individually and do not include reconstitution supplies, syringes, or aliquoting tools. Products ship in lyophilized (freeze-dried) form and require proper reconstitution before use in research settings. See our Reconstitution Solution page for laboratory-grade bacteriostatic water.
Research use only — not for human or animal consumption. See our Research Use Disclaimer.
